Breast cancer subtypes and outcome after local and regional relapse.
نویسندگان
چکیده
منابع مشابه
Breast cancer subtypes and outcome after local and regional relapse.
BACKGROUND To evaluate the outcome of breast cancer patients after locoregional recurrence (LRR) according to tumor biological features evaluated at first diagnosis and at the time of recurrence. PATIENTS AND METHODS We collected information on all consecutive breast cancer patients operated at the European Institute of Oncology between 1994 and 2005. The tumor characteristics and subsequent ...
متن کاملBreast cancer subtypes and the risk of local and regional relapse.
PURPOSE The risk of local and regional relapse associated with each breast cancer molecular subtype was determined in a large cohort of patients with breast cancer. Subtype assignment was accomplished using a validated six-marker immunohistochemical panel applied to tissue microarrays. PATIENTS AND METHODS Semiquantitative analysis of estrogen receptor (ER), progesterone receptor (PR), Ki-67,...
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Abstract Introduction: Breast cancer is the most common cancer among women. Even though mastectomy is known as a highly effective method to treat breast cancer, the percentage of patients with local recurrence is still high. Objective: To determine the incidence of local recurrence after mastectomy and breast preservation surgery. Materials and Methods: Patients with breast cancer that under...
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Patients with isolated locoregional recurrences of breast cancer have a high risk of distant metastasis and death from cancer. The main objective in this clinical setting is curative treatment, which consists of radical surgery with or without complementary radiotherapy. The targeted localisations include soft tissue of the ipsilateral conserved breast or of the chest wall, mastectomy scar or s...
متن کاملTwo distinct local relapse subtypes in invasive breast cancer: effect on their prognostic impact.
PURPOSE Local relapse (LR) remains an important concern in breast cancer surveillance. Given the unique opportunity to study local recurrences in the breast in the absence of irradiation, we tested the possibility of identifying a particular tumor feature that might account for LR. EXPERIMENTAL DESIGN Archival specimens from 235 patients belonging to the control arm (no radiotherapy) of the M...
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ژورنال
عنوان ژورنال: Journal of Clinical Oncology
سال: 2011
ISSN: 0732-183X,1527-7755
DOI: 10.1200/jco.2011.29.15_suppl.1076